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Gorka J, Marona P, Kwapisz O, Waligórska A, Pospiech E, Dobrucki JW, Rys J, Jura J, Miekus K MCPIP1 inhibits Wnt/β-catenin signaling pathway activity and modulates epithelial-mesenchymal transition during clear cell renal cell carcinoma progression by targeting miRNAs Oncogene. 2021 Oct 16. doi: 10.1038/s41388-021-02062-3. PMID: 34657130. PDF available here.


Zarebski M, Bosire R, Wesolowska J, Szelest O, Eatmann A, Jasinska-Konior K, Kepp O, Kroemer G, Szabo G, Dobrucki JW. Translocation of chromatin proteins to nucleoli-The influence of protein dynamics on post-fixation localization Cytometry Part A. 2021 Jun. doi: 10.1002/cyto.a.24464. Epub 2021 Jun. PDF available here.



Kordon M, Zarębski M, Solarczyk K, Ma H, Pederson T, Dobrucki J. STRIDE - a fluorescence method for direct, specific in situ detection of individual single- or double-strand DNA breaks in fixed cells Nucleic Acid Research. 2020 Feb;48(3):e14. doi: 10.1093/nar/gkz1118. Epub 2019 Nov. PubMed PMID: 31832687. PDF available here.


Kordon M. et al., PML-like subnuclear bodies, containing XRCC1, juxtaposed to DNA replication-based single-strand breaks FASEB J. 2019 Feb;33(2):2301-2313. doi: 10.1096/fj.201801379R. Epub 2018 Sep 27. PMID: 30260704. PDF available here.


Szczurek A, Contu F, Hoang A, Dobrucki J, Mai S., Aqueous mounting media increasing tissue translucence improve image quality in Structured Illumination Microscopy of thick biological specimen. Scientific Reports. 2018 Sep 18;8(1):13971. doi: 10.1038/s41598-018-32191-x. PMID: 30228281. PDF available here.

Greb-Markiewicz B, Zarębski M, Ożyhar A., Multiple sequences orchestrate subcellular trafficking of neuronal PAS domain-containing protein 4 (NPAS4). Journal of Biological Chemistry. 2018 Jul 20;293(29):11255-11270. doi: 10.1074/jbc.RA118.001812. Epub 2018 Jun 13. PMID: 29899116. PDF available here.

Orłowski M, Popławska K, Pieprzyk J, Szczygieł-Sommer A, Więch A, Zarębski M, Tarczewska A, Dobrucki J, Ożyhar A., Molecular determinants of Drosophila immunophilin FKBP39 nuclear localization. Biol Chem. 2018 Feb 6. pii: /j/bchm.ahead-of-print/hsz-2017-0251/hsz-2017-0251.xml. doi: 10.1515/hsz-2017-0251. [Epub ahead of print]. PMID: 29337690. PDF available here.

Szczurek A, Birk U, Knecht H, Dobrucki J, Mai S, Cremer C., Super-resolution binding activated localization microscopy through reversible change of DNA conformation. Nucleus. 2018 Jan 1;9(1):182-189. doi: 10.1080/19491034.2017.1419846. PMID: 2929724. PDF available here.


Pellefigues C, Tang SC, Schmidt A, White RF, Lamiable O, Connor LM, Ruedl C, Dobrucki J, Le Gros G, Ronchese F., Toll-Like Receptor 4, but Not Neutrophil Extracellular Traps, Promote IFN Type I Expression to Enhance Th2 Responses to Nippostrongylus brasiliensis, Front Immunol. 2017 Nov 16;8:1575. doi: 10.3389/fimmu.2017.01575. eCollection 2017. PMID: 29201030. PDF available here


Dobrucki J, Saitoh N., The 4D nucleome in Kraków - Prospects for an emerging field, Nucleus. 2017 Sep 3;8(5):447-448. doi: 10.1080/19491034.2017.1347243. PMID: 28745542. PDF available here.


Bzowska M, Nogieć A, Bania K, Zygmunt M, Zarębski M, Dobrucki J, Guzik K., Involvement of cell surface 90 kDa heat shock protein (HSP90) in pattern recognition by human monocyte-derived macrophages, J Leukoc Biol. 2017 Sep;102(3):763-774. doi: 10.1189/jlb.2MA0117-019R. Epub 2017 May 26. PubMedID: 28550115. PDF available here.


Przybyło M, Drabik D, Szostak K, Borowik T, Klösgen B, Dobrucki J, Sikorski AF, Langner M., Changes in lipid membrane mechanics induced by di- and tri-phenyltins, Biochim Biophys Acta. 2017 Aug;1859(8):1301-1309. doi: 10.1016/j.bbamem.2017.04.025. Epub 2017 Apr 29. PMID: 28461050. PDF available here.


Szewczyk M, Fedoryszak-Kuśka N, Tkaczuk K, Dobrucki J, Waligórska A, Stępień PP., Human SUV3 helicase regulates growth rate of the HeLa cells and can localize in the nucleoli, Acta Biochim Pol. 2017; 64(1):177-181. doi: 10.18388/abp.2016_1419. Epub 2017 Mar 15. PMID: 28291845. PDF available here.


Szczurek A, Klewes L, Xing J, Gourram A, Birk U, Knecht H, Dobrucki JW, Mai S, Cremer C., Imaging chromatin nanostructure with binding-activated localization microscopy based on DNA structure fluctuations, Nucleic Acids Res. 2017 May 5; 45(8):e56. doi: 10.1093/nar/gkw1301. PMID: 28082388. PDF available here.


Borowczyk-Michalowska J, Zimolag E, Waligorska A, Dobrucki J, Madeja Z, Drukala J., Stage-specific embryonic antigen-4 as a novel marker of ductal cells of human eccrine sweat glands, Br J Dermatol. 2017 Jun; 176(6):1541-1548. doi: 10.1111/bjd.15154. Epub 2017 Apr 5. PMID: 27797400. PDF available here



Pierzyńska-Mach A, Szczurek A, Cella Zanacchi F, Pennacchietti F, Drukała J, Diaspro A, Cremer C, Darzynkiewicz Z, Dobrucki JW. Subnuclear localization, rates and effectiveness of UVC-induced unscheduled DNA synthesis visualized by fluorescence widefield, confocal and super-resolution microscopy. Cell Cycle. 2016;15(8):1156-67. doi: 10.1080/15384101.2016.1158377. PMID: 27097376. PDF available here.

Rybak P, Hoang A, Bujnowicz L, Bernas T, Berniak K, Zarębski MA, Darzynkiewicz Z, Dobrucki J. Low level phosphorylation of histone H2AX on serine 139 (γH2AX) is not associated with DNA double-strand breaks. Oncotarget. 2016 Jul 6. doi: 10.18632/oncotarget. PMID: 27391338. PDF available here.

Żurek-Biesiada D, Szczurek AT, Prakash K, Mohana GK, Lee HK, Roignant JY, Birk UJ, Dobrucki JW, Cremer C., Localization microscopy of DNA in situ using Vybrant(®) DyeCycle™ Violet fluorescent probe: A new approach to study nuclear nanostructure at single molecule resolution. Exp Cell Res. 2016 May 1;343(2):97-106. doi: 10.1016/j.yexcr.2015.08.020. Epub 2015 Sep 1. PMID: 26341267. PDF available here.

Solarczyk K, Wojcik K, Kulakowski P. Nanocommunication via FRET With DyLight Dyes Using Multiple Donors and Acceptors. IEEE Trans Nanobioscience. 2016 Apr;15(3):275-83. doi: 10.1109/TNB.2016.2541462. PMID: 27071184. PDF available here.

Przybylo M, Glogocka D, Dobrucki JW, Fraczkowska K, Podbielska H, Kopaczynska M, Borowik T, Langner M., The cellular internalization of liposome encapsulated protoporphyrin IX by HeLa cells. Eur J Pharm Sci. 2016 Mar 31;85:39-46. doi: 10.1016/j.ejps.2016.01.028. Epub 2016 Jan 28. PMID: 26827924. PDF available here.

Żurek-Biesiada D, Szczurek AT, Prakash K, Best G, Mohana GK, Lee HK, Roignant JY, Dobrucki JW, Cremer C, Birk U., Quantitative super-resolution localization microscopy of DNA in situ using Vybrant® DyeCycle™ Violet fluorescent probe. Data Brief. 2016 Jan 29;7:157-71. doi: 10.1016/j.dib.2016.01.041. eCollection 2016 Jun. PMID: 27054149. PDF available here.

Solarczyk KJ, Kordon M, Berniak K, Dobrucki JW. Two stages of XRCC1 recruitment and two classes of XRCC1 foci formed in response to low level DNA damage induced by visible light, or stress triggered by heat shock. DNA Repair. 2016 Jan;37: 12-21. doi: 10.1016/j,dnarep.2015.10.006. PubMedID: 26630398. PDF available here.



Stec M, Szatanek R, Baj-Krzyworzeka M, Baran J, Zembala M, Barbasz J, Waligórska A, Dobrucki JW, Mytar B, Szczepanik A, Siedlar M, Drabik G, Urbanowicz B, Zembala M., Interactions of tumour-derived micro(nano)vesicles with human gastric cancer cells. J Transl Med. 2015 Dec 1;13:376. doi: 10.1186/s12967-015-0737-0. PMID: 26626416. PDF available here

Rybak P, Waligórska A, Bujnowicz Ł, Hoang A., Dobrucki J. Activation of new replication foci under conditions of replication stress. Cell Cycle. 2015;14(16): 2634-47. doi: 10.1080/15384101.2015.1064566. PMID: 26212617. PDF available here.

Wojcik K, Solarczyk K, Kułakowski P. Measurements on MIMO-FRET nano-networks based on Alexa Fluor dyes. IEEE Transactions on Nanotechnology. 2015 Mar 20. doi: 10.1109/TNANO.2015.2415201. PDF available here.


Zuwała K, Golda A, Kabala W, Burmistrz M, Zdzalik M, Nowak P, Kedracka-Krok S, Zarebski M, Dobrucki J, Florek D, Zeglen S, Wojarski J, Potempa J, Dubin G, Pyrc K. The nucleocapsid protein of human coronavirus NL63. PLoS One. 2015 Feb 20;10(2):e0117833. doi: 10.1371/journal.pone.0117833. PMID: 25700263. PDF available here.


Shishova KV, Lavrentyeva EA, Dobrucki JW, Zatsepina OV. Nucleolus-like bodies of fully-grown mouse oocytes contain key nucleolar proteins but are impoverished for rRNA. Dev Biol. 2015 Jan 15;397(2):267-81. doi: 10.1016/j.ydbio.2014.11.022. PMID: 25481757. PDF available here.


Piwowarczyk K, Wybieralska E, Baran J, Borowczyk J, Rybak P, Kosińska M, Włodarczyk AJ, Michalik M, Siedlar M, Madeja Z, Dobrucki J, Reiss K, Czyż J. Fenofibrate enhances barrier function of endothelial continuum within the metastatic niche of prostate cancer cells. Expert Opin Ther Targets. 2015 Feb;19(2):163-76. doi: 10.1517/14728222.2014.981153. PMID: 25389904. PDF available here.





Żurek-Biesiada D, Waligórski P, Dobrucki JW. UV-induced spectral shift and protonation of DNA fluorescent dye Hoechst 33258. J Fluoresc. 2014 Nov;24(6):1791-801. doi: 10.1007/s10895-014-1468-y. PMID: 25312832. PDF available here.


Li B, Zhao H, Rybak P, Dobrucki JW, Darzynkiewicz Z, Kimmel M. Different rates of DNA replication at early versus late S-phase sections: multiscale modeling of stochastic events related to DNA content/EdU (5-ethynyl-2'deoxyuridine) incorporation distributions. Cytometry A. 2014 Sep;85(9):785-97. doi: 10.1002/cyto.a.22484. PMID: 24894899. PDF available here.


Pierzyńska-Mach A, Janowski PA, Dobrucki JW. Evaluation of acridine orange, LysoTracker Red, and quinacrine as fluorescent probes for long-term tracking of acidic vesicles. Cytometry A. 2014 Aug;85(8):729-37. doi: 10.1002/cyto.a.22495. PMID: 24953340. PDF available here.


Bernas T, Brutkowski W, Zarębski M, Dobrucki J. Spatial heterogeneity of dynamics of H1 linker histone. Eur Biophys J. 2014 Jul;43(6-7):287-300. doi: 10.1007/s00249-014-0962-0. PMID: 24830851. PDF available here.


Aggarwal C, Banaś AK, Kasprowicz-Maluśki A, Borghetti C, Labuz J, Dobrucki J, Gabryś H. Blue-light-activated phototropin2 trafficking from the cytoplasm to Golgi/post-Golgi vesicles. J Exp Bot. 2014 Jul;65(12):3263-76. doi: 10.1093/jxb/eru172. PMID: 24821953. PDF available here.


Szczurek AT, Prakash K, Lee HK, Zurek-Biesiada DJ, Best G, Hagmann M, Dobrucki JW, Cremer C, Birk U. Single molecule localization microscopy of the distribution of chromatin using Hoechst and DAPI fluorescent probes. Nucleus. 2014 Jul-Aug;5(4):331-40. doi: 10.4161/nucl.29564. PMID: 25482122. PDF available here.


Zarębski M, Kordon M, Dobrucki JW. Photosensitized damage inflicted on plasma membranes of live cells by an extracellular generator of singlet oxygen--a linear dependence of a lethal dose on light intensity. Photochem Photobiol. 2014 May-Jun;90(3):709-15. doi: 10.1111/php.12216. PMID: 24279807. PDF available here.





Zhao H, Halicka HD, Li J, Biela E, Berniak K, Dobrucki J, Darzynkiewicz Z. DNA damage signaling, impairment of cell cycle progression, and apoptosis triggered by 5-ethynyl-2'-deoxyuridine incorporated into DNA. Cytometry A. 2013 Nov;83(11):979-88. doi: 10.1002/cyto.a.22396. PMID: 24115313. PDF available here.


Bernas T, Berniak K, Rybak P, Zarębski M, Zhao H, Darzynkiewicz Z, Dobrucki JW. Analysis of spatial correlations between patterns of DNA damage response and DNA replication in nuclei of cells subjected to replication stress or oxidative damage. Cytometry A. 2013 Oct;83(10):925-32. doi: 10.1002/cyto.a.22325. PMID: 23900967. PDF available here.


Berniak K, Rybak P, Bernas T, Zarębski M, Biela E, Zhao H, Darzynkiewicz Z, Dobrucki JW. Relationship between DNA damage response, initiated by camptothecin or oxidative stress, and DNA replication, analyzed by quantitative 3D image analysis. Cytometry A. 2013 Oct;83(10):913-24. doi: 10.1002/cyto.a.22327. PMID: 23846844. PDF available here.


Wlodkowic D, Akagi J, Dobrucki J, Errington R, Smith PJ, Takeda K, Darzynkiewicz Z. Kinetic viability assays using DRAQ7 probe. Curr Protoc Cytom. 2013 Jul;Chapter 9:Unit 9.41. doi: 10.1002/0471142956.cy0941s65. PMID: 23835805. PDF available here.


Wójcik K, Zarębski M, Cossarizza A, Dobrucki JW. Daunomycin, an antitumor DNA intercalator, influences histone-DNA interactions. Cancer Biol Ther. 2013 Sep;14(9):823-32. doi: 10.4161/cbt.25328. PMID: 23792590. PDF available here.


Zurek-Biesiada D, Kędracka-Krok S, Dobrucki JW. UV-activated conversion of Hoechst 33258, DAPI, and Vybrant DyeCycle fluorescent dyes into blue-excited, green-emitting protonated forms. Cytometry A. 2013 May;83(5):441-51. doi: 10.1002/cyto.a.22260. PMID: 23418106. PDF available here.


Biela E, Galas J, Lee B, Johnson GL, Darzynkiewicz Z, Dobrucki JW. Col-F, a fluorescent probe for ex vivo confocal imaging of collagen and elastin in animal tissues. Cytometry A. 2013 Feb 12. doi: 10.1002/cyto.a.22264. PMID: 23404939. PDF available here.

Trembecka-Lucas DO, Szczurek AT, Dobrucki JW. Dynamics of the HP1β-PCNA-containing complexes in DNA replication and repair. Nucleus. 2013 Jan 1;4(1). PMID: 23337132. PDF available here.

Akagi J, Kordon M, Zhao H, Matuszek A, Dobrucki J, Errington R, Smith PJ, Takeda K, Darzynkiewicz Z, Wlodkowic D. Real-time cell viability assays using a new anthracycline derivative DRAQ7. Cytometry A. 2013 Feb;83(2):227-34. doi: 10.1002/cyto.a.22228. PMID: 23165976. PDF available here.



Darzynkiewicz Z, Zhao H, Halicka HD, Rybak P, Dobrucki J, Wlodkowic D. DNA damage signaling assessed in individual cells in relation to the cell cycle phase and induction of apoptosis. Crit Rev Clin Lab Sci. 2012 Sep-Dec;49(5-6):199-217. doi: 10.3109/10408363.2012.738808. PMID: 23137030. PDF available here.

Solarczyk KJ, Zarębski M, Dobrucki JW. Inducing local DNA damage by visible light to study chromatin repair. DNA Repair (Amst). 2012 Dec 1;11(12):996-1002. doi: 10.1016/j.dnarep.2012.09.008. PMID: 23089313. PDF available here.

Zoglowek A, Orłowski M, Pakuła S, Dutko-Gwóźdź J, Pajdzik D, Gwóźdź T, Rymarczyk G, Wieczorek E, Dobrucki J, Dobryszycki P, Ożyhar A. The composite nature of the interaction between nuclear receptors EcR and DHR38. Biol Chem. 2012 May;393(6):457-71. doi: 10.1515/hsz-2011-0283. PMID: 22628309. PDF available here.

Trembecka-Lucas DO, Dobrucki JW. A heterochromatin protein 1 (HP1) dimer and a proliferating cell nuclear antigen (PCNA) protein interact in vivo and are parts of a multiprotein complex involved in DNA replication and DNA repair. Cell Cycle. 2012 Jun 1;11(11):2170-5. Epub 2012 Jun 1. PMID: 22617335. PDF available here.

Zhao H, Rybak P, Dobrucki J, Traganos F, Darzynkiewicz Z. Relationship of DNA damage signaling to DNA replication following treatment with DNA topoisomerase inhibitors camptothecin/topotecan, mitoxantrone, or etoposide. Cytometry A. 2012 Jan;81(1):45-51. doi: 10.1002/cyto.a.21172. Epub 2011 Dec 2. PMID: 22140093. PDF available here.



Zhao H, Dobrucki J, Rybak P, Traganos F, Dorota Halicka H, Darzynkiewicz Z. Induction of DNA damage signaling by oxidative stress in relation to DNA replication as detected using "click chemistry". Cytometry A. 2011 Nov;79(11):897-902. doi: 10.1002/cyto.a.21137. Epub 2011 Sep 8. PMID: 21905210. PDF available here.

Greb-Markiewicz B, Orłowski M, Dobrucki J, Ożyhar A., Sequences that direct subcellular traffic of the Drosophila methoprene-tolerant protein (MET) are located predominantly in the PAS domains. Mol Cell Endocrinol. 2011 Oct 15;345(1-2):16-26. doi: 10.1016/j.mce.2011.06.035. Epub 2011 Jul 2. PMID: 21745535. PDF available here.

Kedziora KM, Prehn JH, Dobrucki J, Bernas T. Method of calibration of a fluorescence microscope for quantitative studies. J Microsc. 2011 Oct;244(1):101-11. doi: 10.1111/j.1365-2818.2011.03514.x. Epub 2011 Jul 14. PMID: 2175625. PDF available here.

Zubik M, Luchowski R, Grudzinski W, Gospodarek M, Gryczynski I, Gryczynski Z, Dobrucki JW, Gruszecki WI. Light-induced isomerization of the LHCII-bound xanthophyll neoxanthin: possible implications for photoprotection in plants. Biochim Biophys Acta. 2011 Sep;1807(9):1237-43. Epub 2011 Jun 22. PMID: 21718685. PDF available here.

Zhao H, Li J, Traganos F, Halicka HD, Zarebski M, Dobrucki J, Darzynkiewicz Z. Cell fixation in zinc salt solution is compatible with DNA damage response detection by phospho-specific antibodies. Cytometry A. 2011 Jun;79(6):470-6. doi: 10.1002/cyto.a.21060. PMID: 21595014. PDF available here.



Aref'eva AS, Dyban PA, Krasil'shchikova MS, Dobrucki JW, Zatsepina OV. Localization and composition of renal immunodeposits in mice developing HgCl2-induced autoimmune process. Tsitologiia. 2010;52(6):477-86. PUMBED ID: 20737906. PDF available here.

Cytometry A. 2010 Apr;77(4):399-405. Rationale for the real-time and dynamic cell death assays using propidium iodide. Zhao H, Oczos J, Janowski P, Trembecka D, Dobrucki J, Darzynkiewicz Z, Wlodkowic D. PMID: 20131407. PDF available here.

Trembecka DO, Kuzak M, Dobrucki JW. Conditions for using FRAP as a quantitative technique--influence of the bleaching protocol. Cytometry A. 2010 Apr;77(4):366-70. PMID: 20131402. PDF available here.

Mikołajczyk TP, Skrzeczyńska-Moncznik JE, Zarebski MA, Marewicz EA, Wiśniewska AM, Dzieba M, Dobrucki JW, Pryjma JR. Interaction of human peripheral blood monocytes with apoptotic polymorphonuclear cells. Immunology. 2009 Sep;128(1):103-13. PMID: 19689740. PDF available here.

Zarebski M, Wiernasz E, Dobrucki JW. Recruitment of heterochromatin protein 1 to DNA repair sites. Cytometry A. 2009 Jul;75(7):619-25. PMID: 19479850. PDF available here.

Luijsterburg MS, Dinant C, Lans H, Stap J, Wiernasz E, Lagerwerf S, Warmerdam DO, Lindh M, Brink MC, Dobrucki JW, Aten JA, Fousteri MI, Jansen G, Dantuma NP, Vermeulen W, Mullenders LH, Houtsmuller AB, Verschure PJ, van Driel R. Heterochromatin protein 1 is recruited to various types of DNA damage. J Cell Biol. 2009 May 18;185(4):577-86. PMID: 19451271. PDF available here.  

Zhao H, Traganos F, Dobrucki J, Wlodkowic D, Darzynkiewicz Z. Induction of DNA damage response by the supravital probes of nucleic acids. Cytometry A. 2009 Jun;75(6):510-9. PMID: 19373929. PDF available here.

Łukasiewicz S, Faron-Górecka A, Dobrucki J, Polit A, Dziedzicka-Wasylewska M. Studies on the role of the receptor protein motifs possibly involved in electrostatic interactions on the dopamine D1 and D2 receptor oligomerization. FEBS J. 2009 Feb;276(3):760-75. PMID: 19143836. PDF available here.

Dutko-Gwóźdź J, Gwóźdź T, Orłowski M, Greb-Markiewicz B, Duś D, Dobrucki J, Ozyhar A. The variety of complexes formed by EcR and Usp nuclear receptors in the nuclei of living cells. Mol Cell Endocrinol. 2008 Nov 6;294(1-2):45-51. Epub 2008 Aug 14. PMID: 18771703. PDF available here.

Wojcik K, Dobrucki JW. Interaction of a DNA intercalator DRAQ5, and a minor groove binder SYTO17, with chromatin in live cells--influence on chromatin organization and histone-DNA interactions. Cytometry A. 2008 Jun;73(6):555-62. PMID: 18459157. PDF available here.

Zhao H, Tanaka T, Halicka HD, Traganos F, Zarebski M, Dobrucki J, Darzynkiewicz Z. Cytometric assessment of DNA damage by exogenous and endogenous oxidants reports aging-related processes. Cytometry A. 2007 Nov;71(11):905-14. PMID: 17879239. PDF available here.

Rajwa B, Bernas T, Acker H, Dobrucki J, Robinson JP. Single- and two-photon spectral imaging of intrinsic fluorescence of transformed human hepatocytes. Microsc Res Tech. 2007 Oct;70(10):869-79. PMID: 17661363. PDF available here.

Dobrucki JW, Feret D, Noatyńska A. Scattering of exciting light by live cells in fluorescence confocal imaging: phototoxic effects and relevance for FRAP studies. Biophys J. 2007 Sep 1;93(5):1778-86. Epub 2007 Apr 6. PMID: 17416613. PDF available here.

Krzeszowiec W, Rajwa B, Dobrucki J, Gabryś H. Actin cytoskeleton in Arabidopsis thaliana under blue and red light. Biol Cell. 2007 May;99(5):251-60. PMID: 17253958. PDF available here.

Gwóźdź T, Dutko-Gwóźdź J, Nieva C, Betańska K, Orłowski M, Kowalska A, Dobrucki J, Spindler-Barth M, Spindler KD, Ozyhar A. EcR and Usp, components of the ecdysteroid nuclear receptor complex, exhibit differential distribution of molecular determinants directing subcellular trafficking. Cell Signal. 2007 Mar;19(3):490-503. Epub 2006 Aug 22. PMID: 17011166. PDF available here.



Garstka M, Drozak A, Rosiak M, Venema JH, Kierdaszuk B, Simeonova E, van Hasselt PR, Dobrucki J, Mostowska A. Light-dependent reversal of dark-chilling induced changes in chloroplast structure and arrangement of chlorophyll-protein complexes in bean thylakoid membranes. Biochim Biophys Acta. 2005 Nov 15;1710(1):13-23. Epub 2005 Sep 15. PMID: 16209864. PDF available here.

Nieva C, Gwóźdź T, Dutko-Gwóźdź J, Wiedenmann J, Spindler-Barth M, Wieczorek E, Dobrucki J, Duś D, Henrich V, Ozyhar A, Spindler KD. Ultraspiracle promotes the nuclear localization of ecdysteroid receptor in mammalian cells. Biol Chem. 2005 May;386(5):463-70. PMID: 15927890. PDF available here.

Bernas T, Asem EK, Robinson JP, Cook PR, Dobrucki JW. Confocal fluorescence imaging of photosensitized DNA denaturation in cell nuclei. Photochem Photobiol. 2005 Jul-Aug;81(4):960-9. PMID: 15884971. PDF available here.

Wolnicka-Głubisz A, Rajwa B, Dobrucki J, Skrzeczyńska-Moncznik J, van Henegouwen GB, Sarna T. Phototoxicity, distribution and kinetics of association of UVA-activated chlorpromazine, 8-methoxypsoralen, and 4,6,4'-trimethylangelicin in Jurkat cells. J Photochem Photobiol B. 2005 Feb 1;78(2):155-64. PMID: 15664503. PDF available here.

Dobrucki JW. Confocal microscopy: quantitative analytical capabilities. Methods Cell Biol. 2004;75:41-72. PMID: 15603422

Czyz J, Rajwa B, Bzowska M, Dobrucki J, Korohoda W. Spreading-independent growth of normal fibroblasts in three-dimensional cultures. Folia Biol (Krakow). 2004;52(1-2):19-24. PMID: 15521643. PDF available here.

Bernas T, Dobrucki JW. Backscattered light confocal imaging of intracellular MTT-formazan crystals. Microsc Res Tech. 2004 Jun 1;64(2):126-34. PMID: 15352083.

Bernas T, Zarebski M, Dobrucki JW, Cook PR. Minimizing photobleaching during confocal microscopy of fluorescent probes bound to chromatin: role of anoxia and photon flux. J Microsc. 2004 Sep;215(Pt 3):281-96. PMID: 15312193. PDF available here.

Pinti M, Troiano L, Nasi M, Ferraresi R, Dobrucki J, Cossarizza A. Hepatoma HepG2 cells as a model for in vitro studies on mitochondrial toxicity of antiviral drugs: which correlation with the patient? J Biol Regul Homeost Agents. 2003 Apr-Jun;17(2):166-71. PMID: 14518717

Debska G, Kicinska A, Dobrucki J, Dworakowska B, Nurowska E, Skalska J, Dolowy K, Szewczyk A. Large-conductance K+ channel openers NS1619 and NS004 as inhibitors of mitochondrial function in glioma cells. Biochem Pharmacol. 2003 Jun 1;65(11):1827-34. PMID: 12781334. PDF available here.

Kołcz J, Rajwa B, Drukała J, Dobrucki J, Korohoda W, Malec E. Three-dimensional visualization of connexin 43 on the human cardiomyocytes. Appl Immunohistochem Mol Morphol. 2002 Sep;10(3):247-52. PMID: 12373152.

Garcia Fernandez M, Troiano L, Moretti L, Nasi M, Pinti M, Salvioli S, Dobrucki J, Cossarizza A. Early changes in intramitochondrial cardiolipin distribution during apoptosis. Cell Growth Differ. 2002 Sep;13(9):449-55. PMID: 12354754. PDF available here.

Bernas T, Dobrucki J. Mitochondrial and nonmitochondrial reduction of MTT: interaction of MTT with TMRE, JC-1, and NAO mitochondrial fluorescent probes. Cytometry. 2002 Apr 1;47(4):236-42. PMID: 11933013. PDF available here.

Dobrucki JW. Interaction of oxygen-sensitive luminescent probes Ru(phen)(3)(2+) and Ru(bipy)(3)(2+) with animal and plant cells in vitro. Mechanism of phototoxicity and conditions for non-invasive oxygen measurements. J Photochem Photobiol B. 2001 Dec 31;65(2-3):136-44. PMID: 11809371. PDF available here.

Czyz J, Dobrucki J, Korohoda W. Anchorage-dependent chick embryo fibroblasts synthesise DNA and proliferate when cultured in multilayered sheets suspended among glass fibres. Folia Biol (Krakow). 2001;49(1-2):1-12. PMID: 11732159.

Dobrucki J, Darzynkiewicz Z. Chromatin condensation and sensitivity of DNA in situ to denaturation during cell cycle and apoptosis--a confocal microscopy study. Micron. 2001 Oct;32(7):645-52. PMID: 11334733. PDF available here.

Kasza A, Rogowski K, Kilarski W, Sobota R, Bernas T, Dobrucki J, Travis J, Koj A, Bugno M, Kordula T. Differential effects of oncostatin M and leukaemia inhibitory factor expression in astrocytoma cells. Biochem J. 2001 Apr 15;355(Pt 2):307-14. PMID: 11284716. PDF available here.

Tworzydło M, Laczka M, Rajwa B, Dobrucki J, Turyna B. Evaluation of biocompatibility of apatite-wollastonite ceramics in fibroblast cultures. Folia Histochem Cytobiol. 2000;38(3):133-41. PMID: 10970073.

Bernas T, Dobrucki JW. The role of plasma membrane in bioreduction of two tetrazolium salts, MTT, and CTC. Arch Biochem Biophys. 2000 Aug 1;380(1):108-16. PMID: 10900139. PDF available here.

Salvioli S, Dobrucki J, Moretti L, Troiano L, Fernandez MG, Pinti M, Pedrazzi J, Franceschi C, Cossarizza A. Mitochondrial heterogeneity during staurosporine-induced apoptosis in HL60 cells: analysis at the single cell and single organelle level. Cytometry. 2000 Jul 1;40(3):189-97. PMID: 10878561. PDF available here.

Salvioli S, Barbi C, Dobrucki J, Moretti L, Pinti M, Pedrazzi J, Pazienza TL, Bobyleva V, Franceschi C, Cossarizza A. Opposite role of changes in mitochondrial membrane potential in different apoptotic processes. FEBS Lett. 2000 Mar 10;469(2-3):186-90. PMID: 10713268. PDF available here.



Bernas T, Dobrucki J. Reduction of a tetrazolium salt, CTC, by intact HepG2 human hepatoma cells: subcellular localisation of reducing systems. Biochim Biophys Acta. 1999 Aug 12;1451(1):73-81. PMID: 10446389. PDF available here.

Guzik K, Bzowska M, Dobrucki J, Pryjma J. Heat-shocked monocytes are resistant to Staphylococcus aureus-induced apoptotic DNA fragmentation due to expression of HSP72. Infect Immun. 1999 Aug;67(8):4216-22. PMID: 10417194. PDF available here.

Bernas T, Dobrucki J. Extracellular reduction of Cat1 free radical by transformed human hepatocytes. Biosci Rep. 1998 Dec;18(6):341-50. PMID: 10357176. PDF available here.

Jaruga E, Salvioli S, Dobrucki J, Chrul S, Bandorowicz-Pikuła J, Sikora E, Franceschi C, Cossarizza A,Bartosz G. Apoptosis-like, reversible changes in plasma membrane asymmetry and permeability, and transient modifications in mitochondrial membrane potential induced by curcumin in rat thymocytes. FEBS Lett. 1998 Aug 21;433(3):287-93. PMID: 9744813. PDF available here.



Dobrucki JW, Sutherland RM, Swartz HM. Nonperturbing test for cytotoxicity in isolated cells and spheroids, using electron paramagnetic resonance. Magn Reson Med. 1991 May;19(1):42-55. PMID: 1646372.

Dobrucki JW, Demsar F, Walczak T, Woods RK, Bacic G, Swartz HM. Electron spin resonance microscopy of an in vitro tumour model. Br J Cancer. 1990 Feb;61(2):221-4. PMID: 2155641. PDF available here.

Woods, R.K., Dobrucki, J.W., Glockner, J.F.,Morse Jr., P.D., Swartz, H.M. Spectral-spatial ESR imaging as a method of noninvasive biological oximetry; 1989, Journal of Magnetic Resonance, 85(1), pp. 50-5. [link]

Nettleton DO, Morse PD 2nd, Dobrucki JW, Swartz HM, Dodd NJ. Distribution of 5-doxylstearic acid in the membranes of mammalian cells. Biochim Biophys Acta. 1988 Oct 6;944(2):315-20. PMID: 2846059.

Dobrucki JW, Riley PA. The stoichiometry of tyrosinase-catalyzed oxidation of 4-hydroxyanisole. Free Radic Res Commun. 1988;4(5):325-9. PMID: 2853110. PDF available here.

Dobrucki J, Bleehen NM.  Cell-cell contact affects cellular sensitivity to hyperthermia. Br J Cancer. 1985 Dec;52(6):849-55. PMID: 3935150. PDF available here.