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PhD student

A position for a PhD candidate is open for a highly motivated person to join our research group at Department of Cell Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University in Kraków, Poland. The stipend is funded by Polish National Science Centre (NCN). The successful candidate will participate in a project which is focused on mechanisms of DNA damage induction and repair in mammalian oocytes and somatic cells. Cell biology and biophysical techniques will be used, including fluorescence confocal and super-resolution imaging, and various methods of detection of DNA damage and repair.

The overall goal of the proposal is to improve our understanding of the mechanisms behind lower mutation rates of the female germline in comparison with somatic cells. The planned research involves direct measurements the numbers of endogenous single-strand DNA breaks  (STRIDE technique, Nucl. Acids Res. 2020), measurements and imaging of localisation of critical SSB repair factors in oocytes and somatic cells, assessing the capacity of oocytes and zygotes to repair SSBs, and measurements of abundance of repair components and assessing their role in conferring resistance to DNA damage.

Candidates are encouraged to contact the project principal investigator (jerzy.dobrucki@uj.edu.pl) regarding further details about the planned research activities.

The ideal candidate should have basic knowledge about cell biology and biophysics, and good command of spoken and written English.

More information about the Cell Biophysics Department is available at: https://helios.wbbib.uj.edu.pl/en_GB/home

 

Schedule of the competition:

  • Application submission deadline: 26th May 2022
  • Entrance exams: 2nd June 2022
  • Announcement of results: 13th June 2022
  • Enrollment: 16th-28th June 2022

All candidates are kindly requested to send a cv to professor Jerzy Dobrucki at: jerzy.dobrucki@uj.edu.pl. The selected candidate will be informed about further administrative steps leading towards enrolling in a Doctoral School.

Insurance:

Students admitted to the Doctoral School are covered by health insurance, retirement, disability and accident insurance.